There are many different influenza vaccines formulations licensed for use in the U.S., including inactivated (killed virus) vaccines that are injected into muscle or into skin, a recombinant (engineered protein) vaccine that is injected into muscle, and a live attenuated (disabled virus) vaccine that is sprayed into the nose. The choice of vaccine formulation depends upon several factors, including age, comorbidities, and risk of adverse reaction. CDC does not preferentially recommend any particular licensed age-appropriate vaccine formulation.
RECOMMENDATIONS:
- For ages 6 months and older, inactivated injectable formulations are available and dosed based on age. For ages 2 years to 49 years, the attenuated FluMist Quadrivalent intranasal vaccine is an alternative. (Quadrivalent means having four ingredients.)
- Healthy, nonpregnant adults between 18 and 49 years of age can take an inactivated vaccine or the live attenuated influenza vaccine.
- Women in any stage of pregnancy are encouraged to take an inactivated injectable influenza vaccine, which can protect a woman from flu during and after pregnancy, and also protect her baby from flu for several months after birth.
- For individuals between 50 and 64 years of age, inactivated influenza vaccines are available.
- Individuals ages 65 years or older can take the high-dose inactivated influenza vaccine (Fluzone High-Dose Quadrivalent) when available. An alternative is the quadrivalent recombinant vaccine (Flublok Quadrivalent).